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Yayin da COVID na dogon lokaci yana riƙe da asirai da yawa, masu bincike sun sami alamu ga alamun cututtukan zuciya na gama gari a cikin waɗannan marasa lafiya, suna ba da shawarar cewa kumburi mai tsayi mai shiga tsakani ne.
A cikin rukunin 346 marasa lafiya na COVID-19 a baya lafiya, yawancinsu sun kasance alamun alamun bayan tsaka-tsaki na kusan watanni 4, haɓakawa a cikin alamun cututtukan cututtukan zuciya da rauni na zuciya ko rashin aiki sun kasance da wuya.
Amma akwai alamu da yawa na matsalolin zuciya na subclinical, rahoton Valentina O. Puntmann, MD, Asibitin Jami'ar Frankfurt, Jamus, da takwarorinta a Nature Medicine.
Idan aka kwatanta da abubuwan sarrafa marasa lafiya, marasa lafiya na COVID suna da hauhawar jini na diastolic sosai, yana ƙaruwa da yawa marasa ischemic myocardial scaring saboda haɓakar gadolinium na ƙarshen, bugun jini mara-hemodynamically mai alaƙa da pericardial, da bugun pericardial.<0,001). <0.001).
Bugu da kari, kashi 73% na marasa lafiya na COVID-19 masu alamun cututtukan zuciya suna da ƙimar taswirar taswirar zuciya ta MRI (CMR) fiye da daidaikun mutane masu asymptomatic, yana nuna kumburin ƙwayar cuta na zuciya da babban tarin bambancin pericardial.
"Abin da muke gani ba shi da kyau," Puntmann ya fada wa MedPage A Yau."Waɗannan marasa lafiya ne na yau da kullun."
Ya bambanta da abin da aka fi tsammanin shine matsalar zuciya tare da COVID-19, waɗannan sakamakon suna ba da haske cewa marasa lafiya da ke da matsalolin zuciya da suka rigaya sun fi yiwuwa a kwantar da su a asibiti tare da mummunar cuta da sakamako.
Ƙungiyar Puntman ta yi nazarin mutanen da ba su da matsalolin zuciya don ƙoƙarin fahimtar tasirin COVID-19 da kanta, ta yin amfani da hotunan MRI na bincike-bincike na marasa lafiya da aka ɗauka zuwa asibitocin su ta hanyar likitocin dangi, cibiyoyin hukumar lafiya, kayan tallatawa da marasa lafiya ke rarraba akan layi.Ƙungiyoyi da gidajen yanar gizo..
Puntmann ya lura cewa yayin da wannan zaɓin ƙungiyar marasa lafiya ne waɗanda ƙila ba gabaɗaya suna wakiltar lokuta masu sauƙi na COVID-19 ba, ba sabon abu ba ne ga waɗannan marasa lafiya su nemi amsoshin alamun su.
Bayanan binciken tarayya ya nuna cewa kashi 19 cikin 100 na manya Ba'amurke da suka kamu da cutar COVID suna da alamun cutar tsawon watanni 3 ko fiye bayan kamuwa da cuta.A cikin binciken na yanzu, bin diddigin yana duba matsakaicin watanni 11 bayan kamuwa da cutar COVID-19 ya nuna alamun zuciya na ci gaba a cikin kashi 57% na mahalarta.Wadanda suka kasance masu alamun bayyanar cututtuka suna da ƙwayar ƙwayar ƙwayar ƙwayar cuta fiye da waɗanda suka murmure ko kuma basu da alamun bayyanar cututtuka (na halitta T2 37.9 vs 37.4 da 37.5 ms, P = 0.04).
"Shigar da zuciya wani muhimmin bangare ne na bayyanar dogon lokaci na COVID - don haka dyspnea, rashin haƙuri, tachycardia," in ji Pontman a cikin wata hira.
Ƙungiyarta ta kammala da cewa alamun cututtukan zuciya da suka lura sun kasance "suna da alaƙa da ciwon kumburi na zuciya, wanda zai iya bayyana, aƙalla a wani ɓangare, tushen pathophysiological na ci gaba da bayyanar cututtuka na zuciya.Musamman ma, mummunan rauni na tsokar zuciya ko cututtukan zuciya ba yanayin da aka rigaya ya kasance ba kuma alamun ba su dace da ma'anar gargajiya na myocarditis ba.
Likitan zuciya da kuma mai haƙuri na COVID na dogon lokaci Alice A. Perlowski, MD, ya nuna mahimman abubuwan da ke tattare da asibiti ta hanyar tweeting: “Wannan binciken ya kwatanta yadda masu nazarin halittu na gargajiya (a cikin wannan yanayin CRP, calcin muscle, NT-proBNP) na iya ba da labarin duka. ”., #LongCovid, Ina fatan duk likitocin da suka ga wadannan marasa lafiya a aikace sun magance wannan muhimmin batu."
Daga cikin manya 346 da ke da COVID-19 (ma'anar shekaru 43.3, 52% mata) an duba su a wata cibiya tsakanin Afrilu 2020 da Oktoba 2021, a tsakiyar kwanaki 109 bayan fallasa, mafi yawan alamun cututtukan zuciya shine ƙarancin motsa jiki (62%) ), bugun zuciya (28%), ciwon ƙirji na yau da kullun (27%), da syncope (3%).
"Sanin abin da ke faruwa tare da gwaje-gwajen zuciya na yau da kullum kalubale ne saboda yana da wuya a gano wasu yanayi mara kyau," in ji Puntmann.“Sashe na shi yana da alaƙa da ilimin halittar jiki da ke bayansa… Ko da aikinsu ya lalace, ba abin mamaki bane saboda suna ramawa da tachycardia da zuciya mai cike da zumudi.Don haka, ba mu gan su a cikin matakin da ba a biya ba.”
Ƙungiyar ta yi shirin ci gaba da bin waɗannan marasa lafiya na dogon lokaci don fahimtar abin da zai iya haifar da matsalolin asibiti, suna tsoron cewa "yana iya yin shelar babban nauyin rashin ciwon zuciya shekaru a kan hanya," a cewar shafin yanar gizon cibiyar.Har ila yau, ƙungiyar ta ƙaddamar da binciken MYOFLAME-19 mai sarrafa wuribo don gwada magungunan ƙwayoyin cuta da magungunan da ke aiki akan tsarin renin-angiotensin a cikin wannan yawan.
Nazarin su ya haɗa da marasa lafiya kawai waɗanda ba a san cututtukan zuciya da aka sani ba, cututtuka, ko gwaje-gwajen aikin huhun da ba na al'ada ba a asali kuma waɗanda ba a taɓa kwantar da su a asibiti don tsananin COVID-19 ba.
Ƙarin ƙarin marasa lafiya 95 a asibitin waɗanda ba su da COVID-19 na farko kuma ba su da cututtukan zuciya ko cututtuka an yi amfani da su azaman sarrafawa.Yayin da masu binciken suka yarda cewa za a iya samun bambance-bambancen da ba a san su ba idan aka kwatanta da marasa lafiya na COVID, sun lura da irin wannan rarraba abubuwan haɗari ta hanyar shekaru, jinsi, da cututtukan zuciya.
Daga cikin marasa lafiya da ke da alamun COVID, yawancin masu laushi ne ko matsakaici (38% da 33%, bi da bi), kuma tara (3%) ne kawai ke da alamun bayyanar cututtuka waɗanda ke iyakance ayyukan yau da kullun.
Abubuwan da ke tsinkayar alamun cututtukan zuciya daban-daban daga sikanin asali don sake duba aƙalla watanni 4 (tsakiyar kwanaki 329 bayan ganewar asali) sun kasance jinsin mata kuma suna watsa shigar da zuciya ta zuciya akan tushe.
"Musamman, saboda bincikenmu ya mayar da hankali kan mutanen da ke da cutar ta COVID-19, bai bayar da rahoton yawaitar alamun cututtukan zuciya bayan COVID ba," kungiyar Puntman ta rubuta."Duk da haka, yana ba da mahimman bayanai game da bakan su da juyin halitta na gaba."
Puntmann da co-marubucin sun bayyana kudaden magana daga Bayer da Siemens, da kuma tallafin ilimi daga Bayer da NeoSoft.
Tushen ambato: Puntmann VO et al "Tsarin cututtukan zuciya na dogon lokaci a cikin mutane masu sauƙin fara cutar COVID-19", Nature Med 2022;DOI: 10.1038/s41591-022-02000-0.
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